Panadol Cold and Flu Caplets helps to provide night time relief from cold and flu symptoms. This is a combination of three medicines: Paracetamol, pseudoephedrine and chlorpheniramine, which relieves cold symptoms. Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer). It blocks the release of certain chemical messengers in the brain that are responsible for pain and fever. Pseudoephedrine is a nasal decongestant which narrows the small blood vessels providing relief from congestion or stuffiness in the nose. Chlorpheniramine is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing.